David G Hirst Selected Research

AMD 6221

9/2011

Antitumor actions of ruthenium(III)-based nitric oxide scavengers and nitric oxide synthase inhibitors.

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David G Hirst Research Topics

Disease

18	Neoplasms (Cancer) 01/2015 - 01/2003
3	Prostatic Neoplasms (Prostate Cancer) 04/2011 - 06/2007
2	Hypoxia (Hypoxemia) 03/2013 - 01/2008
2	Breast Neoplasms (Breast Cancer) 02/2011 - 02/2010
2	Carcinogenesis 01/2011 - 02/2009
2	Colonic Neoplasms (Colon Cancer) 06/2007 - 01/2004
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2011
1	Carcinosarcoma 09/2011
1	Fibrosarcoma 04/2011
1	Neoplasm Metastasis (Metastasis) 02/2010
1	Duodenogastric Reflux 02/2009
1	Pathologic Processes 08/2008
1	Wounds and Injuries (Trauma) 03/2008
1	Carcinoma (Carcinomatosis) 06/2007
1	Vomiting 01/2007
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2007
1	Abdominal Aortic Aneurysm 02/2004
1	Laryngeal Neoplasms (Laryngeal Cancer) 01/2004
1	Colorectal Neoplasms (Colorectal Cancer) 01/2004

Drug/Important Bio-Agent (IBA)

4	Pharmaceutical PreparationsIBA 10/2011 - 01/2004
4	Niacinamide (Nicotinamide)FDA LinkGeneric 10/2011 - 01/2004
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2011 - 05/2007
4	Nitric Oxide Synthase (NO Synthase)IBA 09/2011 - 06/2007
2	rucaparibIBA 01/2015 - 10/2009
2	Proteins (Proteins, Gene)FDA Link 01/2012 - 02/2009
2	EnzymesIBA 09/2011 - 08/2008
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 09/2011 - 09/2010
2	Antineoplastic Agents (Antineoplastics)IBA 04/2011 - 05/2007
2	Docetaxel (Taxotere)FDA Link 03/2011 - 01/2004
2	OsteocalcinIBA 09/2010 - 06/2007
2	Hormones (Hormone)IBA 09/2010 - 06/2007
2	AQ4NIBA 03/2008 - 01/2003
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2015
1	nitrogen trioxide (dinitrogen trioxide)IBA 03/2013
1	1- hydroxy- 2- oxo- 3,3- bis(2- aminoethyl)- 1- triazeneIBA 03/2013
1	CaspasesIBA 01/2012
1	GoldIBA 01/2012
1	3-aminobenzamideIBA 10/2011
1	olaparibIBA 10/2011
1	AMD 6221IBA 09/2011
1	acetamidineIBA 09/2011
1	1-amino-2-hydroxyguanidineIBA 09/2011
1	Oxygen (Dioxygen)IBA 09/2011
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 09/2011
1	Platelet Endothelial Cell Adhesion Molecule-1IBA 09/2011
1	Drinking WaterIBA 09/2011
1	ProdrugsIBA 04/2011
1	Ganciclovir (Cytovene)FDA LinkGeneric 04/2011
1	Thymidine KinaseIBA 04/2011
1	Therapeutic UsesIBA 02/2011
1	Biological ProductsIBA 01/2011
1	Estrogen Receptor Modulators (Antiestrogen)IBA 02/2010
1	Estrogens (Estrogen)FDA Link 02/2010
1	Tamoxifen FDA LinkGeneric 02/2010
1	Fulvestrant (Faslodex)FDA Link 02/2010
1	AlbuminsIBA 10/2009
1	1- (4- dimethylaminomethylphenyl)- 8,9- dihydro- 7H- 2,7,9a- benzo(cd)azulen- 6- oneIBA 10/2009
1	Messenger RNA (mRNA)IBA 02/2009
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 02/2009
1	Cisplatin (Platino)FDA LinkGeneric 02/2009
1	NitrogenIBA 08/2008
1	fumagillinIBA 03/2008
1	thiazolyl blueIBA 03/2008
1	N 30IBA 01/2008
1	Glucose (Dextrose)FDA LinkGeneric 01/2008
1	AndrogensIBA 06/2007
1	DNA (Deoxyribonucleic Acid)IBA 06/2007
1	LipidsIBA 06/2007
1	Pentoxifylline (Trental)FDA LinkGeneric 01/2005
1	Vasodilator Agents (Vasodilators)IBA 01/2004
1	Cytochrome P-450 CYP3AIBA 01/2003
1	Complementary DNA (cDNA)IBA 01/2003

Therapy/Procedure

6	Therapeutics 02/2014 - 05/2007
3	Radiotherapy 10/2011 - 01/2004
2	Oxygenators 01/2005 - 01/2004
1	Injections 09/2011
1	Withholding Treatment 09/2011
1	Stents 02/2004
1	Drug Therapy (Chemotherapy) 01/2004